Oligonucleotide Synthesis

Integrated DNA Technologies

Integrated DNA Technologies (IDT), a subsidiary of Danaher Corporation, is the world's largest supplier of custom oligonucleotides, providing DNA and RNA synthesis services and molecular biology reagents to research, clinical, and industrial customers. Founded in 1987 in Coralville, Iowa, IDT has built its leadership position on speed, scale, and quality of synthesis, with the ability to deliver standard oligos within 24 hours at academic discount pricing that has made synthetic DNA accessible to every lab. Their Alt-R CRISPR-Cas9 system, which includes chemically modified guide RNAs and Cas9 ribonucleoprotein complexes, is one of the most widely adopted CRISPR editing tools for both academic and therapeutic research. IDT's xGen hybridization capture panel technology is broadly used for targeted next-generation sequencing applications, including whole exome sequencing and custom gene panel enrichment. Their Ultramer DNA and RNA oligos enable synthesis of long, high-fidelity sequences needed for synthetic biology and gene assembly. IDT also supplies rhAmpSeq amplicon sequencing systems, rhPCR reagents using RNase H2-dependent cleavage for allele-specific genotyping, and a broad range of labeled probes including dual-labeled hydrolysis probes for qPCR. Their SciTools bioinformatics suite provides free design algorithms for primers, probes, and CRISPR guides, cementing researcher loyalty across the workflow.